TargetMol

AZ3976

Product Code:
 
TAR-T23764
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23764-1mg1mg£124.00
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TAR-T23764-5mg5mg£201.00
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Quantity:
TAR-T23764-1mL1 mL * 10 mM (in DMSO)£242.00
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TAR-T23764-10mg10mg£294.00
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TAR-T23764-25mg25mg£543.00
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TAR-T23764-50mg50mg£744.00
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Quantity:
TAR-T23764-100mg100mg£1,002.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZ3976 is a plasminogen activator inhibitor type 1 (PAI-1) inhibitor.
CAS:
1418747-15-5
Formula:
C15H19N5O3
Molecular Weight:
317.349
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)N1CC(C1)Nc1nc2ncccc2c(=O)[nH]1
Target:
PAI-1

References

1. Cazzolli G, Wang F, a Beccara S, Gershenson A, Faccioli P, Wintrode PL. Serpin latency transition at atomic resolution. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15414-9. doi: 10.1073/pnas.1407528111. Epub 2014 Oct 13. PubMed PMID: 25313058; PubMed Central PMCID: PMC4217474. 2. Fjellstr?m O, Deinum J, Sj?gren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. PubMed PMID: 23155046; PubMed Central PMCID: PMC3543036.