TargetMol

Benzolamide

Product Code:
 
TAR-T23782
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23782-5mg5mg£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23782-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T23782-10mg10mg£136.00
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TAR-T23782-25mg25mg£204.00
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Quantity:
TAR-T23782-50mg50mg£270.00
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Quantity:
TAR-T23782-100mg100mg£378.00
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Quantity:
TAR-T23782-200mg200mg£532.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Benzolamide inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
CAS:
3368-13-6
Formula:
C8H8N4O4S3
Molecular Weight:
320.36
Pathway:
Metabolism
Purity:
0.9703
SMILES:
NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccccc2)s1
Target:
Carbonic Anhydrase

References

1. Prete SD, et, al. Escherichia coli ?-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1545-1554. 2. Vullo D, et, al. Sulfonamide Inhibition Studies of the ?-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora. Molecules. 2020 Feb 25;25(5):1036. 3. Pospelov AS, et, al. Carbonic anhydrase inhibitors suppress seizures in a rat model of birth asphyxia. Epilepsia. 2021 Jun 27. 4. Cecchi A, Winum JY, Innocenti A, Vullo D, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5775-80. PubMed PMID: 15501039.