TargetMol

BU-E 75

Product Code:
 
TAR-T23835
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23835-5mg5mg£1,091.00
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TAR-T23835-50mg50mg£2,143.00
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Quantity:
TAR-T23835-100mg100mg£2,801.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
BU-E 75 is an agonist of the histamine H2.
CAS:
114667-74-2
Formula:
C21H24F2N6
Molecular Weight:
398.462
Purity:
0.98
SMILES:
Fc1ccc(cc1F)C(CCNC(=N)NCCCc1c[nH]cn1)c1ccccn1

References

1. Felix SB, Buschauer A, Baumann G. Therapeutic value of H2-receptor stimulation in congestive heart failure. Hemodynamic effects of BU-E-76, BU-E-75 and arpromidine (BU-E-50) in comparison to impromidine. Agents Actions Suppl. 1991;33:257-69. PubMed PMID: 1828932. 2. Buschauer A, Baumann G. Structure-activity relationships of histamine H2-agonists, a new class of positive inotropic drugs. Agents Actions Suppl. 1991;33:231-56. PubMed PMID: 1828931. 3. Rixen D, Neugebauer E, Lechleuthner A, Buschauer A, Nagelschmidt M, Thoma S, Rink A. Beneficial effect of H2-agonism and H1-antagonism in rat endotoxic shock. Shock. 1994 Jul;2(1):47-52. PubMed PMID: 7735983. 4. Bungardt E, Buschauer A, Moser U, Schunack W, Lambrecht G, Mutschler E. Histamine H1 receptors mediate vasodilation in guinea-pig ileum resistance vessels: characterization with computer-assisted videomicroscopy and new selective agonists. Eur J Pharmacol. 1992 Oct 6;221(1):91-8. PubMed PMID: 1459193.