TargetMol

Cularine

Product Code:
 
TAR-T23918
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T23918-5mg5mg£850.00
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Further Information

Bioactivity:
Cularine is an isoquinoline alkaloid from the Fumariaceae family. It displays non-specific antispasmodic activity on guinea-pig and human airways.
CAS:
479-39-0
Formula:
C20H23NO4
Molecular Weight:
341.407
Purity:
0.98
SMILES:
[H][C@@]12Cc3cc(OC)c(OC)cc3Oc3c(OC)ccc(CCN1C)c23

References

1. KAMETANI T, FUKUMOTO K. CULARINE AND RELATED COMPOUNDS. IV. THE OXIMINATION AND REDUCTION OF 2,3,6-TRIMETHOXYDIBENZO(B,F)OXEPIN-10(11H)-ONE. Chem Pharm Bull (Tokyo). 1963 Oct;11:1322-5. PubMed PMID: 14075288. 2. KAMETANI T, FUKUMOTO K, MASUKO K. [SYNTHESIS OF CULARINE AND RELATED COMPOUNDS. VII. THE FORMATION OF INDOLE DERIVATIVES. (STUDIES ON THE SYNTHESES OF HETEROCYCLIC COMPOUNDS. XCI.)]. Yakugaku Zasshi. 1963 Nov;83:1052-5. Japanese. PubMed PMID: 14084791. 3. KAMETANI T, FUKUMOTO K, NAKANO T. [Studies on the syntheses of cularine derivatives. I. A synthesis of diphenyl ether by Ullmann reaction and the formation of oxepine nucleus]. Yakugaku Zasshi. 1962 Sep;82:1307-11. Japanese. PubMed PMID: 13962076. 4. D'Ocon P, Blasco R, Candenas L, Ivorra D, L?pez S, Villaverde C, Castedo L, Cortes D. Inhibition of calcium entry induced by cularines and isocrasifoline in uterine smooth muscle. Eur J Pharmacol. 1991 Apr 17;196(2):183-7. PubMed PMID: 1874285.