TargetMol

Dactylarin

Product Code:
 
TAR-T23953
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T23953-5mg5mg£850.00
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Further Information

Bioactivity:
Dactylarin is a cytotoxic antibiotic. Dactylarin isolated from Dactylaria lutea. Dactylarin interacts with thiols, which explains its inhibitory effect on the above glycolytic enzymes.
CAS:
22350-90-9
Formula:
C16H16O6
Molecular Weight:
304.298
Purity:
0.98
SMILES:
COC1=CC(=O)C=C(C)C11Oc2c(cc(OC)cc2O)C1O

References

1. Sturd?k E, Drobnica L. Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells. J Antibiot (Tokyo). 1981 Jun;34(6):708-12. PubMed PMID: 6456251. 2. Henderson JF, Zombor G, Miko M. Adenosine triphosphate catabolism in Ehrlich ascites tumor cells treated with dactylarin. Biochem Pharmacol. 1980 Aug 1;29(15):2155-8. PubMed PMID: 7190827. 3. Miko M, Drobnica L, Chance B. Inhibition of energy metabolism in Ehrlich ascites cells treated with dactylarin in vitro. Cancer Res. 1979 Oct;39(10):4242-51. PubMed PMID: 476657. 4. Becker AM, Rickards RW, Schmalzl KJ, Yick HC. Metabolites of Dactylaria lutea. The structures of dactylariol and the antiprotozoal antibiotic dactylarin. J Antibiot (Tokyo). 1978 Apr;31(4):324-9. PubMed PMID: 566263.