TargetMol

DDD100097

Product Code:
 
TAR-T23973
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23973-5mg5mg£850.00
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Quantity:
TAR-T23973-50mg50mg£1,661.00
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Quantity:
TAR-T23973-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DDD100097 is an inhibitor of Trypanosoma brucei N-myristoyl transferase. It has markedly improved blood-brain barrier permeability.
CAS:
1215012-74-0
Formula:
C22H30Cl2F2N4O2S
Molecular Weight:
523.46
Purity:
0.98
SMILES:
CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1

References

1. Brand S, Norcross NR, Thompson S,et al. Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis. J Med Chem. 2014 Dec 11;57(23):9855-69. doi: 10.1021/jm500809c. Epub 2014 Nov 20. PubMed PMID: 25412409; PubMed Central PMCID: PMC4269550.