TargetMol

DDRI-18

Product Code:
 
TAR-T23974
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T23974-5mg5mg£850.00
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Quantity:
TAR-T23974-50mg50mg£1,661.00
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Quantity:
TAR-T23974-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DDRI-18 is an inhibitor of nonhomologous end-joining DNA repair following double-strand DNA breaks induced by ionizing radiation.
CAS:
4402-18-0
Formula:
C26H20N6
Molecular Weight:
416.488
Purity:
0.98
SMILES:
Nc1cccc(c1)-c1nc2ccc(cc2[nH]1)-c1ccc2nc([nH]c2c1)-c1cccc(N)c1

References

1. Jun DW, Jeong YS, Kim HJ, Jeong KC, Kim S, Lee CH. Characterization of DDRI-18 (3,3'-(1H,3'H-5,5'-bibenzo[d]imidazole-2,2'-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response. Br J Pharmacol. 2012 Sep;167(1):141-50. doi: 10.1111/j.1476-5381.2012.01977.x. PubMed PMID: 22519567; PubMed Central PMCID: PMC3448919.