TargetMol

DS-5272

Product Code:
 
TAR-T24019
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24019-5mg5mg£2,456.00
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Quantity:
TAR-T24019-50mg50mg£4,874.00
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Quantity:
TAR-T24019-100mg100mg£6,898.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DS-5272 is a potent and orally active inhibitor of p53-MDM2 interaction.
CAS:
1235575-97-9
Formula:
C34H38Cl2F2N6O2S
Molecular Weight:
703.67
Purity:
0.98
SMILES:
CC[C@@H]1CNC2(CC2)CN1C(=O)[C@@H]1C[C@@H](F)CN1C(=O)C1=C(C(C)C)N2[C@H](c3ccc(Cl)c(F)c3)[C@@](C)(N=C2S1)c1ccc(Cl)nc1

References

1. Miyazaki M, Uoto K, Sugimoto Y, Naito H, Yoshida K, Okayama T, Kawato H, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T. Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitor. Bioorg Med Chem. 2015 May 15;23(10):2360-7. doi: 10.1016/j.bmc.2015.03.069. Epub 2015 Mar 31. PubMed PMID: 25882531.