TargetMol

DTS

Product Code:
 
TAR-T24020
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24020-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24020-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24020-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.
CAS:
6493-73-8
Formula:
C14H14S3
Molecular Weight:
278.45
Purity:
0.98
SMILES:
C(SSSCc1ccccc1)c1ccccc1

References

1. Yagdi Efe E, Mazumder A, Lee JY, Gaigneaux A, Radogna F, Nasim MJ, Christov C, Jacob C, Kim KW, Dicato M, Chaimbault P, Cerella C, Diederich M. Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer. Cancer Lett. 2017 Dec 1;410:139-157. doi: 10.1016/j.canlet.2017.09.011. Epub 2017 Sep 21. PubMed PMID: 28943451. 2. Gutierrez RMP, Hoyo-Vadillo C. Anti-inflammatory Potential of Petiveria alliacea on Activated RAW264.7 Murine Macrophages. Pharmacogn Mag. 2017 Jul;13(Suppl 2):S174-S178. doi: 10.4103/pm.pm_479_16. Epub 2017 Jul 11. PubMed PMID: 28808377; PubMed Central PMCID: PMC5538151. 3. Murray J, Picking D, Lamm A, McKenzie J, Hartley S, Watson C, Williams L, Lowe H, Delgoda R. Significant inhibitory impact of dibenzyl trisulfide and extracts of Petiveria alliacea on the activities of major drug-metabolizing enzymes in vitro: An assessment of the potential for medicinal plant-drug interactions. Fitoterapia. 2016 Jun;111:138-46. doi: 10.1016/j.fitote.2016.04.011. Epub 2016 Apr 20. PubMed PMID: 27105957. 4. Lowe HI, Facey CO, Toyang NJ, Bryant JL. Specific RSK kinase inhibition by dibenzyl trisulfide and implication for therapeutic treatment of cancer. Anticancer Res. 2014 Apr;34(4):1637-41. PubMed PMID: 24692692.