TargetMol

Fusarochromanone

Product Code:
 
TAR-T24075
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24075-5mg5mg£1,251.00
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TAR-T24075-50mg50mg£2,464.00
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Quantity:
TAR-T24075-100mg100mg£3,283.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fusarochromanone is a melanoma growth inhibitor.
CAS:
802915-53-3
Formula:
C15H20N2O4
Molecular Weight:
292.335
Purity:
0.98
SMILES:
CC1(C)CC(=O)c2c(N)c(ccc2O1)C(=O)C[C@@H](N)CO

References

1. El-Saadi MW, Williams-Hart T, Salvatore BA, Mahdavian E. Use of in-silico assays to characterize the ADMET profile and identify potential therapeutic targets of fusarochromanone, a novel anti-cancer agent. In Silico Pharmacol. 2015 Dec;3(1):6. doi: 10.1186/s40203-015-0010-5. Epub 2015 Jun 4. PubMed PMID: 26820891; PubMed Central PMCID: PMC4464579. 2. Gu Y, Barzegar M, Chen X, Wu Y, Shang C, Mahdavian E, Salvatore BA, Jiang S, Huang S. Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5. Oncotarget. 2015 Dec 8;6(39):42322-33. doi: 10.18632/oncotarget.5996. PubMed PMID: 26517353; PubMed Central PMCID: PMC4747228. 3. Gu Y, Chen X, Shang C, Singh K, Barzegar M, Mahdavian E, Salvatore BA, Jiang S, Huang S. Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells. PLoS One. 2014 Nov 10;9(11):e112641. doi: 10.1371/journal.pone.0112641. eCollection 2014. PubMed PMID: 25384025; PubMed Central PMCID: PMC4226581. 4. Mahdavian E, Palyok P, Adelmund S, Williams-Hart T, Furmanski BD, Kim YJ, Gu Y, Barzegar M, Wu Y, Bhinge KN, Kolluru GK, Quick Q, Liu YY, Kevil CG, Salvatore BA, Huang S, Clifford JL. Biological activities of fusarochromanone: a potent anti-cancer agent. BMC Res Notes. 2014 Sep 3;7:601. doi: 10.1186/1756-0500-7-601. PubMed PMID: 25187308; PubMed Central PMCID: PMC4168212.