TargetMol

JM-1232

Product Code:
 
TAR-T24201
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T24201-5mg5mg£1,171.00
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Quantity:
TAR-T24201-50mg50mg£2,303.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24201-100mg100mg£3,042.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.
CAS:
1013427-48-9
Formula:
C24H27N3O2
Molecular Weight:
389.499
Purity:
0.98
SMILES:
CN1CCN(CC1)C(=O)C[C@H]1N(C(=O)c2cc3CCCc3cc12)c1ccccc1

References

1. Suneja A, Bisai V, Singh VK. Asymmetric Syntheses of Medicinally Important Isoindolinones (S)-PD 172938, (R)-JM 1232, and Related Structures. J Org Chem. 2016 Jun 3;81(11):4779-88. doi: 10.1021/acs.joc.6b00770. Epub 2016 May 17. PubMed PMID: 27148957. 2. Iwata K, Iida H, Iida M, Fukuoka N, Kito K, Tanabe K. Effects of topical and intravenous JM-1232(-) infusion on cerebrovascular reactivity in rats. J Anesth. 2015 Oct;29(5):798-802. doi: 10.1007/s00540-015-2017-9. Epub 2015 Apr 26. PubMed PMID: 25913256. 3. Ikemoto K, Ishiyama T, Shintani N, Asano N, Sessler DI, Matsukawa T. The effects of topical and intravenous JM-1232(-) on cerebral pial microvessels of rabbits. BMC Anesthesiol. 2015 Mar 20;15:37. doi: 10.1186/s12871-015-0016-x. eCollection 2015. PubMed PMID: 25805961; PubMed Central PMCID: PMC4372327. 4. Ogura T, Hamada T, Matsui T, Tanaka S, Okabe S, Kazama T, Kobayashi Y. Neuroprotection by JM-1232(-) against oxygen-glucose deprivation-induced injury in rat hippocampal slice culture. Brain Res. 2015 Jan 12;1594:52-60. doi: 10.1016/j.brainres.2014.10.038. Epub 2014 Oct 31. PubMed PMID: 25451121.