TargetMol

JNJ-28610244

Product Code:
 
TAR-T24207
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24207-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24207-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24207-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.
CAS:
1251462-28-8
Formula:
C16H21N3O
Molecular Weight:
271.364
Purity:
0.98
SMILES:
CN1CCC(CC1)C(=NO)c1cc2cc(C)ccc2[nH]1

References

1. Dib K, Perecko T, Jenei V, McFarlane C, Comer D, Brown V, Katebe M, Scheithauer T, Thurmond RL, Chazot PL, Ennis M. The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. J Leukoc Biol. 2014 Sep;96(3):411-8. doi: 10.1189/jlb.2AB0813-432RR. Epub 2014 May 5. PubMed PMID: 24799603; PubMed Central PMCID: PMC5395935. 2. Desai P, Thurmond RL. Histamine H? receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation. Eur J Immunol. 2011 Jun;41(6):1764-73. doi: 10.1002/eji.201040932. Epub 2011 May 25. PubMed PMID: 21469095.