TargetMol

JTE 7-31

Product Code:
 
TAR-T24218
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24218-5mg5mg£930.00
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Quantity:
TAR-T24218-50mg50mg£1,821.00
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Quantity:
TAR-T24218-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JTE 7-31 is a selective agonist of the cannabinoid receptor. It is a reasonably highly selective CB2 agonist (Ki: 0.088 nM at CB2 vs 11 nM at CB1).
CAS:
194358-72-0
Formula:
C22H28N2O3
Molecular Weight:
368.477
Purity:
0.98
SMILES:
CCCCCNc1c2CN(CCc3ccc(O)cc3)C(=O)c2ccc1OC

References

1. Zhou EH, Paolucci M, Dryja TP, Manley T, Xiang C, Rice DS, Prasanna G, Chen A. A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):2991-3003. doi: 10.1167/iovs.16-20974. PubMed PMID: 28605810. 2. Salort G, ?lvaro-Bartolom? M, Garc?a-Sevilla JA. Regulation of cannabinoid CB(2) receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain. Psychopharmacology (Berl). 2017 Mar;234(6):925-941. doi: 10.1007/s00213-017-4537-5. Epub 2017 Jan 26. PubMed PMID: 28127623.