TargetMol

P 22077

Product Code:
 
TAR-T2424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2424-2mg2mg£96.00
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TAR-T2424-5mg5mg£112.00
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TAR-T2424-10mg10mg£137.00
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TAR-T2424-1mL1 mL * 10 mM (in DMSO)£144.00
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TAR-T2424-25mg25mg£205.00
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TAR-T2424-50mg50mg£327.00
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Quantity:
TAR-T2424-100mg100mg£453.00
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Further Information

Bioactivity:
P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.
CAS:
1247819-59-5
Formula:
C12H7F2NO3S2
Molecular Weight:
315.32
Pathway:
Ubiquitination; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Purity:
0.9842
SMILES:
CC(=O)c1cc(c(Sc2c(F)cc(F)cc2)s1)[N+](=O)[O-]
Target:
DUB

References

1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173. 2. Altun M, et al. Chem Biol, 2011, 18(11), 1401-1412. 3. Chen F, Zhang W, Xie D, et al. Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters[J. Nucleic Acids Research. 2020, 48(18): 10211-10225.