TargetMol

Kapurimycin A3

Product Code:
 
TAR-T24247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T24247-5mg5mg£850.00
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Further Information

Bioactivity:
Kapurimycin A3 is an antitumor antibiotics.
CAS:
129966-45-6
Formula:
C30H41NO4
Molecular Weight:
479.66
Purity:
0.98
SMILES:
O=C(O)C(CC)[C@H]1CC[C@H](C)[C@H](/C(CC)=C/C=C/C2[C@@H](C(C3=CC=CN3)=O)[C@]4([H])CCC[C@@]4([H])C=C2)O1

References

1. Sugiyama H, Lam CK, Hosoda M, Saito I. Site specific covalent alkylation of DNA by antitumor antibiotics, duocarmycin A and kapurimycin A3. Nucleic Acids Symp Ser. 1991;(25):75-6. PubMed PMID: 1842103. 2. Hara M, Yoshida M, Nakano H. Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3. Biochemistry. 1990 Nov 20;29(46):10449-55. PubMed PMID: 2271655. 3. Chan KL, Sugiyama H, Saito I, Hara M. NMR characterization of guanine DNA site alkylated by kapurimycin A3, an antitumour antibiotic from Streptomyces sp. Phytochemistry. 1995 Nov;40(5):1373-4. PubMed PMID: 8534399. 4. Okamoto A, Nakatani K, Saito I. Studies on the mechanism of DNA sequence selective alkylation by kapurimycin A3 analogs. Nucleic Acids Symp Ser. 1997;(37):27-8. PubMed PMID: 9585982.