TargetMol

KMS88009

Product Code:
 
TAR-T24265
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24265-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24265-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24265-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.
CAS:
1089681-42-4
Formula:
C19H19NO2
Molecular Weight:
293.366
Purity:
0.98
SMILES:
COc1ccc2cc(C=Cc3ccc(cc3)N(C)C)oc2c1

References

1. Brener O, Dunkelmann T, Gremer L, van Groen T, Mirecka EA, Kadish I, Willuweit A, Kutzsche J, J?rgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelt F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. QIAD assay for quantitating a compound's efficacy in elimination of toxic A? oligomers. Sci Rep. 2015 Sep 23;5:13222. doi: 10.1038/srep13222. PubMed PMID: 26394756; PubMed Central PMCID: PMC4585794. 2. Lee SH, Kim Y, Kim HY, Kim YH, Kim MS, Kong JY, Lee MH, Kim DJ, Ahn YG. Aminostyrylbenzofuran directly reduces oligomeric amyloid-? and reverses cognitive deficits in Alzheimer transgenic mice. PLoS One. 2014 Apr 23;9(4):e95733. doi: 10.1371/journal.pone.0095733. eCollection 2014. PubMed PMID: 24760018; PubMed Central PMCID: PMC3997483.