TargetMol

L 648051

Product Code:
 
TAR-T24304
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T24304-5mg5mg£850.00
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Quantity:
TAR-T24304-50mg50mg£1,661.00
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Quantity:
TAR-T24304-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
L 648051 is a leukotriene D4 receptor antagonist.
CAS:
91541-18-3
Formula:
C24H28O8S
Molecular Weight:
476.54
Purity:
0.98
SMILES:
CCCc1c(O)c(ccc1OCCCS(=O)(=O)c1ccc(cc1)C(=O)CCC(O)=O)C(C)=O

References

1. G?k S, Ulker S, Evin? A. Possible contribution of leukotrienes in the arrhythmogenic effects of digoxin on isolated guinea-pig hearts. Pharmacology. 1998 Nov;57(5):279-84. PubMed PMID: 9742293. 2. G?k S, Banoaglu N. Effects of a leukotriene D4 receptor antagonist, L-648,051, and a dual inhibitor lypoxygenase and cyclooxygenase, BW-755C, on digoxin-induced arrhythmias in guinea-pigs. Arch Int Pharmacodyn Ther. 1993 Jan-Feb;321:72-80. PubMed PMID: 8391788. 3. Rasmussen JB, Eriksson LO, Tagari P, Margolskee DJ, Girard Y, Andersson KE. Urinary LTE4 excretion in antigen-provoked asthmatic patients treated with the inhaled LTD4 antagonist, L-648,051. Allergy. 1992 Dec;47(6):599-603. PubMed PMID: 1337423. 4. Rasmussen JB, Eriksson LO, Tagari P, Stahl EG, Andersson KE. Reduced nonspecific bronchial reactivity and decreased airway response to antigen challenge in atopic asthmatic patients treated with the inhaled leukotriene D4 antagonist, L-648,051. Allergy. 1992 Dec;47(6):604-9. PubMed PMID: 1285568.