TargetMol

L 669083

Product Code:
 
TAR-T24322
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24322-5mg5mg£850.00
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Quantity:
TAR-T24322-50mg50mg£1,661.00
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Quantity:
TAR-T24322-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.
CAS:
130007-52-2
Formula:
C29H29IN4O5S
Molecular Weight:
672.54
Purity:
0.98
SMILES:
CC(C)c1ccc2n(Cc3ccc(O)c(I)c3)c(CC(C)(C)C(O)=O)c(c2c1)S(=O)(=O)c1ccc(cc1)N=[N+]=[N-]

References

1. Vickers PJ, Adam M, Charleson S, Coppolino MG, Evans JF, Mancini JA. Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Jul;42(1):94-102. PubMed PMID: 1635556. 2. Mancini JA, Prasit P, Coppolino MG, Charleson P, Leger S, Evans JF, Gillard JW, Vickers PJ. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Feb;41(2):267-72. PubMed PMID: 1538707. 3. Reid GK, Kargman S, Vickers PJ, Mancini JA, L?veill? C, Ethier D, Miller DK, Gillard JW, Dixon RA, Evans JF. Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis. J Biol Chem. 1990 Nov 15;265(32):19818-23. PubMed PMID: 2174053. 4. Miller DK, Gillard JW, Vickers PJ, Sadowski S, L?veill? C, Mancini JA, Charleson P, Dixon RA, Ford-Hutchinson AW, Fortin R, et al. Identification and isolation of a membrane protein necessary for leukotriene production. Nature. 1990 Jan 18;343(6255):278-81. PubMed PMID: 2300172.