TargetMol

EPZ011989

Product Code:
 
TAR-T2435
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2435-5mg5mg£112.00
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TAR-T2435-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T2435-10mg10mg£132.00
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TAR-T2435-100mg100mg£377.00
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This product comes from: United States.
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Further Information

Bioactivity:
EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
CAS:
1598383-40-4
Formula:
C35H51N5O4
Molecular Weight:
605.824
Pathway:
Chromatin/Epigenetic
Purity:
0.9981
SMILES:
CCN([C@H]1CC[C@@H](CC1)N(C)CCOC)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C#CCN1CCOCC1
Target:
Histone Methyltransferase

References

1. Campbell JE, et al. ACS Med Chem Lett. 2015 Mar 4;6(5):491-495.