TargetMol

L 741671

Product Code:
 
TAR-T24357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24357-5mg5mg£850.00
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Quantity:
TAR-T24357-50mg50mg£1,661.00
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Quantity:
TAR-T24357-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
L 741671 is an antagonist of the neurokinin-1 receptor.
CAS:
187724-85-2
Formula:
C23H22F6N4O2
Molecular Weight:
500.445
Purity:
0.98
SMILES:
FC(F)(F)c1cc(CO[C@@H]2CCCN(Cc3nc(=O)[nH][nH]3)[C@@H]2c2ccccc2)cc(c1)C(F)(F)F

References

1. Tattersall FD, Rycroft W, Francis B, Pearce D, Merchant K, MacLeod AM, Ladduwahetty T, Keown L, Swain C, Baker R, Cascieri M, Ber E, Metzger J, MacIntyre DE, Hill RG, Hargreaves RJ. Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets. Neuropharmacology. 1996;35(8):1121-9. PubMed PMID: 9121615.