TargetMol

L-97-1

Product Code:
 
TAR-T24384
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24384-5mg5mg£1,332.00
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Quantity:
TAR-T24384-50mg50mg£2,625.00
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Quantity:
TAR-T24384-100mg100mg£3,524.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
L-97-1 is an antagonist of the adenosine A1 receptor.
CAS:
770703-20-3
Formula:
C29H38N6O3
Molecular Weight:
518.662
Purity:
0.98
SMILES:
CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc(Cc3ccccc3)n(CCN(CC)CCO)c2c1=O

References

1. Wilson CN, Vance CO, Lechner MG, Matuschak GM, Lechner AJ. Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis. Eur J Pharmacol. 2014 Oct 5;740:346-52. doi: 10.1016/j.ejphar.2014.07.012. Epub 2014 Jul 18. PubMed PMID: 25041842; PubMed Central PMCID: PMC4147868. 2. Cullen L, Parsonage WA, Greenslade J, Lamanna A, Hammett CJ, Than M, Tate J, Kalinowski L, Ungerer JP, Chu K, Brown A. Delta troponin for the early diagnosis of AMI in emergency patients with chest pain. Int J Cardiol. 2013 Oct 3;168(3):2602-8. doi: 10.1016/j.ijcard.2013.03.044. Epub 2013 Apr 10. PubMed PMID: 23582689. 3. Wilson CN, Vance CO, Doyle TM, Brink DS, Matuschak GM, Lechner AJ. A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis. Innate Immun. 2012 Jun;18(3):373-89. doi: 10.1177/1753425911411595. Epub 2011 Aug 23. PubMed PMID: 21862597; PubMed Central PMCID: PMC3362682. 4. Rehman S, Lloyd-Jones DM, Martinez-Rumayor A, Januzzi JL. Inflammatory markers, amino-terminal pro-brain natriuretic peptide, and mortality risk in dyspneic patients. Am J Clin Pathol. 2008 Aug;130(2):305-11. doi: 10.1309/L7BP57F7UF7YNYKX. PubMed PMID: 18628102.