TargetMol

Mitochonic Acid 35

Product Code:
 
TAR-T24470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24470-5mg5mg£850.00
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TAR-T24470-50mg50mg£1,661.00
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Quantity:
TAR-T24470-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.
CAS:
1611470-23-5
Formula:
C19H19NO5
Molecular Weight:
341.363
Purity:
0.98
SMILES:
COc1cc(COc2ccc3[nH]cc(CC(O)=O)c3c2)cc(OC)c1

References

1. Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-? and TGF-?(1) pathways. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. PubMed PMID: 28507324; PubMed Central PMCID: PMC5432497.