TargetMol

MK-8141

Product Code:
 
TAR-T24478
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24478-5mg5mg£1,091.00
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TAR-T24478-50mg50mg£2,143.00
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Quantity:
TAR-T24478-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK-8141 is a renin inhibitor. It displays some antihypertensive efficacy in hypertensive patients.
CAS:
903579-36-2
Formula:
C35H39Cl2N3O3
Molecular Weight:
620.62
Purity:
0.98
SMILES:
[H][C@@]12CNC[C@@]([H])(N1)C(C(=O)N(Cc1cccc(C)c1C)C1CC1)=C(C2)c1ccc(OCCOc2c(Cl)cc(C)cc2Cl)cc1

References

1. Jones-Burton C, Rubino J, Roy S, Mai Y, Meehan A, Bellet M, Feig P. Effects of the renin inhibitor MK-8141 (ACT-077825) in patients with hypertension. J Am Soc Hypertens. 2010 Sep-Oct;4(5):219-26. doi: 10.1016/j.jash.2010.06.006. Epub 2010 Aug 12. PubMed PMID: 20705534. 2. Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2009 Jun;31(5):341-56. PubMed PMID: 19649342.