TargetMol

CH-223191

Product Code:
 
TAR-T2448
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2448-5mg5mg£115.00
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Quantity:
TAR-T2448-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T2448-10mg10mg£149.00
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TAR-T2448-25mg25mg£213.00
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TAR-T2448-50mg50mg£308.00
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Quantity:
TAR-T2448-100mg100mg£484.00
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Quantity:
TAR-T2448-200mg200mg£664.00
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Quantity:
TAR-T2448-500mg500mg£994.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
CAS:
301326-22-7
Formula:
C19H19N5O
Molecular Weight:
333.395
Pathway:
Immunology/Inflammation; Metabolism
Purity:
0.9958
SMILES:
Cc1ccccc1N=Nc1ccc(NC(=O)c2ccnn2C)c(C)c1
Target:
AhR; Aryl Hydrocarbon Receptor

References

1. Kim SH, et al. Mol Pharmacol. 2006, 69(6), 1871-1878. 2. Gramatzki D, et al. Oncogene. 2009, 28(28), 2593-2605. 3. Xie HQ, et al. Environ Health Perspect. 2013, 121(5), 613-618. 4. de Souza AR, et al. Toxicol Sci. 2014, 140(1), 204-223. 5. Wang K, Lv Q, Miao Y, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[J]. Biochemical pharmacology. 2018 Sep;155:494-509.