Nimolinone

Product Code:

TAR-T24534

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T24534-5mg

5mg

£850.00

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Quantity:

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Further Information

Bioactivity:

Nimolinone is presented in EENL. EENL by regulating the genes involved in cellular development and cell death functions could control cell proliferation, attenuate the stimulatory effects of VEGF, and exert antiangiogenic effects. EENL treatment could have a potential therapeutic role during cancer progression.

CAS:

106533-51-1

Formula:

C30H42O4

Molecular Weight:

466.662

Purity:

0.98

SMILES:

[H][C@@]12CC(OC(=O)[C@H]1C[C@@H](O)C=C(C)C)[C@]1(C)C3=CC[C@@]4([H])C(C)(C)C(=O)CC[C@]4(C)C3=CC[C@@]21C

Documents

References

1. Mahapatra S, Young CY, Kohli M, Karnes RJ, Klee EW, Holmes MW, Tindall DJ, Donkena KV. Antiangiogenic Effects and Therapeutic Targets of Azadirachta indica Leaf Extract in Endothelial Cells. Evid Based Complement Alternat Med. 2012;2012:303019. doi: 10.1155/2012/303019. Epub 2012 Feb 22. PubMed PMID: 22461839; PubMed Central PMCID: PMC3296311. 2. Mahapatra S, Karnes RJ, Holmes MW, Young CY, Cheville JC, Kohli M, Klee EW, Tindall DJ, Donkena KV. Novel molecular targets of Azadirachta indica associated with inhibition of tumor growth in prostate cancer. AAPS J. 2011 Sep;13(3):365-77. doi: 10.1208/s12248-011-