TargetMol

Norbormide

Product Code:
 
TAR-T24541
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24541-5mg5mg£850.00
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TAR-T24541-50mg50mg£1,661.00
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Quantity:
TAR-T24541-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Norbormide is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker.
CAS:
991-42-4
Formula:
C33H25N3O3
Molecular Weight:
511.581
Purity:
0.98
SMILES:
OC(C1=CC2C3C(C1C2=C(/c1ccccc1)c1ccccn1)C(=O)NC3=O)(c1ccccc1)c1ccccn1

References

1. D'Amore C, Orso G, Fusi F, Pagano MA, Miotto G, Forgiarini A, De Martin S, Castellani G, Ribaudo G, Rennison D, Brimble MA, Hopkins B, Ferrarese A, Bova S. An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging. Front Pharmacol. 2016 Sep 23;7:315. eCollection 2016. PubMed PMID: 27721792; PubMed Central PMCID: PMC5034647. 2. Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D. Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide. Chem Biodivers. 2016 Jun;13(6):762-75. doi: 10.1002/cbdv.201500241. Epub 2016 Jun 2. PubMed PMID: 27144301. 3. Rennison D, Laita O, Conole D, Jay-Smith M, Knauf J, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide. Bioorg Med Chem. 2013 Sep 15;21(18):5886-99. doi: 10.1016/j.bmc.2013.06.071. Epub 2013 Jul 10. PubMed PMID: 23920483. 4. Rennison D, Laita O, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Design and synthesis of prodrugs of the rat selective toxicant norbormide. Bioorg Med Chem. 2012 Jul 1;20(13):3997-4011. doi: 10.1016/j.bmc.2012.05.014. Epub 2012 May 15. PubMed PMID: 22658693.