TargetMol

PIK-90

Product Code:
 
TAR-T2461
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2461-5mg5mg£102.00
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TAR-T2461-10mg10mg£108.00
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TAR-T2461-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T2461-25mg25mg£139.00
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TAR-T2461-50mg50mg£189.00
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This product comes from: United States.
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Further Information

Bioactivity:
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .
CAS:
677338-12-4
Formula:
C18H17N5O3
Molecular Weight:
351.366
Pathway:
DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Purity:
0.9962
SMILES:
COc1ccc2C3=NCCN3C(NC(=O)c3cccnc3)=Nc2c1OC
Target:
DNA-PK; PI3K

References

1. Van Keymeulen A, et al. J Cell Biol. 2006, 174(3), 437-445. 2. Fan QW, et al. Cancer Res. 2007, 67(17), 7960-7965. 3. Niedermeier M, et al. Blood. 2009, 113(22), 5549-5557. 4. Knight ZA, et al. Cell. 2006, 125(4), 733-747.