TargetMol

Piroheptine HCl

Product Code:
 
TAR-T24645
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24645-5mg5mg£930.00
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TAR-T24645-50mg50mg£1,821.00
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Quantity:
TAR-T24645-100mg100mg£2,319.00
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Further Information

Bioactivity:
Piroheptine HCl is an agent of anticholinergic that acts by inhibiting dopamine uptake and completely preventing loss of striatal dopamine in MPTP-treated mice.
CAS:
16378-22-6
Formula:
C22H26ClN
Molecular Weight:
339.91
Purity:
0.98
SMILES:
Cl.CCN1CCC(C1C)=C1c2ccccc2CCc2ccccc12

References

1. Katayama S, Ishizaki F, Yamamura Y, Khoriyama T, Kito S. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990 Sep;69(3):261-70. PubMed PMID: 2236897. 2. Otani K, Hirano T, Kondo T, Kaneko S, Fukushima Y, Noda K, Tashiro Y. Biperiden and piroheptine do not affect the serum level of zotepine, a new antipsychotic drug. Br J Psychiatry. 1990 Jul;157:128-30. PubMed PMID: 1975759. 3. Saitoh T. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. J Neurol Sci. 1988 Feb;83(2-3):161-6. PubMed PMID: 3258627. 4. Ohashi T, Akita H, Tamura T, Noda K, Honda F. Effect of piroheptine, a new antiparkinson drug, on dopamine uptake into synaptosomes from corpus striatum of rat brain. Arzneimittelforschung. 1972 Jun;22(6):966-72. PubMed PMID: 5068358.