TargetMol

RA-2

Product Code:
 
TAR-T24701
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24701-5mg5mg£850.00
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Quantity:
TAR-T24701-50mg50mg£1,661.00
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Quantity:
TAR-T24701-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries.
CAS:
1867107-62-7
Formula:
C22H16F2O6
Molecular Weight:
414.361
Purity:
0.98
SMILES:
Oc1ccc(cc1F)C(=O)OCc1cccc(COC(=O)c2ccc(O)c(F)c2)c1

References

1. Uttley L, Bermejo I, Ren S, Martyn-St James M, Wong R, Scott DL, Young A, Stevenson M. Tofacitinib for Treating Rheumatoid Arthritis After the Failure of Disease-Modifying Anti-rheumatic Drugs: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. Pharmacoeconomics. 2018 Mar 15. doi: 10.1007/s40273-018-0639-0. [Epub ahead of print] Review. PubMed PMID: 29546668. 2. Sato A, Lyamzina Y. Diversity of Concerns in Recovery after a Nuclear Accident: A Perspective from Fukushima. Int J Environ Res Public Health. 2018 Feb 16;15(2). pii: E350. doi: 10.3390/ijerph15020350. Review. PubMed PMID: 29462905; PubMed Central PMCID: PMC5858419. 3. Singh JA, Hossain A, Mudano AS, Tanjong Ghogomu E, Suarez-Almazor ME, Buchbinder R, Maxwell LJ, Tugwell P, Wells GA. Biologics or tofacitinib for people with rheumatoid arthritis naive to methotrexate: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2017 May 8;5:CD012657. doi: 10.1002/14651858.CD012657. Review. PubMed PMID: 28481462. 4. Edwards CJ, Fautrel B, Schulze-Koops H, Huizinga TWJ, Kruger K. Dosing down with biologic therapies: a systematic review and clinicians' perspective. Rheumatology (Oxford). 2017 Nov 1;56(11):1847-1856. doi: 10.1093/rheumatology/kew464. Review. Erratum in: Rheumatology (Oxford). 2018 Mar 1;57(3):589. PubMed PMID: 28339632; PubMed Central PMCID: PMC5850865.