TargetMol

Rimcazole

Product Code:
 
TAR-T24712
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T24712-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24712-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24712-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Rimcazole is a sigma receptor antagonist. It also binds to the dopamine transporter and inhibiting dopamine uptake.
CAS:
75859-04-0
Formula:
C21H27N3
Molecular Weight:
321.468
Purity:
0.98
SMILES:
C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1

References

1. Jayant RD, Atluri VSR, Tiwari S, Pilakka-Kanthikeel S, Kaushik A, Yndart A, Nair M. Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: towards the treatment of NeuroAIDS. J Neurovirol. 2017 Aug;23(4):603-614. doi: 10.1007/s13365-017-0538-8. Epub 2017 Jul 31. PubMed PMID: 28762183; PubMed Central PMCID: PMC5623083. 2. DeLarge AF, Erwin LL, Winsauer PJ. Atypical binding at dopamine and serotonin transporters contribute to the discriminative stimulus effects of mephedrone. Neuropharmacology. 2017 Jun;119:62-75. doi: 10.1016/j.neuropharm.2017.04.006. Epub 2017 Apr 7. PubMed PMID: 28396142. 3. Kaushik A, Vabbina PK, Atluri V, Shah P, Vashist A, Jayant RD, Yandart A, Nair M. Electrochemical monitoring-on-chip (E-MoC) of HIV-infection in presence of cocaine and therapeutics. Biosens Bioelectron. 2016 Dec 15;86:426-431. doi: 10.1016/j.bios.2016.06.086. Epub 2016 Jun 29. PubMed PMID: 27419908; PubMed Central PMCID: PMC5028277. 4. Happy M, Dejoie J, Zajac CK, Cortez B, Chakraborty K, Aderemi J, Sauane M. Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation. Biochem Biophys Res Commun. 2015 Jan 9;456(2):683-8. doi: 10.1016/j.bbrc.2014.12.029. Epub 2014 Dec 13. PubMed PMID: 25511708.