TargetMol

Ro 04-6790 dihydrochloride

Product Code:
 
TAR-T24716
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24716-5mg5mg£850.00
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TAR-T24716-50mg50mg£1,661.00
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Quantity:
TAR-T24716-100mg100mg£2,079.00
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Further Information

Bioactivity:
Ro 04-6790 dihydrochloride is an effective and selective antagonist of the serotonin 5-HT6 receptor.
CAS:
1197333-95-1
Formula:
C12H18Cl2N6O2S
Molecular Weight:
381.28
Purity:
0.98
SMILES:
Cl.Cl.CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1

References

1. Eguibar JR, Cortes Mdel C, Lara-Lozano M, Mendiola DM. Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague-Dawley rats. Pharmacol Biochem Behav. 2012 Jul;102(1):118-23. doi: 10.1016/j.pbb.2012.03.020. Epub 2012 Mar 31. PubMed PMID: 22497991. 2. Yoshizawa K, Narita M, Mori T, Miyatake M, Isotani K, Tomiyasu S, Tsukiyama Y, Suzuki T. Role of dopamine D2 and D3 receptors in mediating the U-50,488H discriminative cue: comparison with methamphetamine and cocaine. Addict Biol. 2012 Nov;17(6):949-55. doi: 10.1111/j.1369-1600.2010.00257.x. Epub 2010 Nov 4. PubMed PMID: 21054688. 3. Maina FK, Mathews TA. A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum. ACS Chem Neurosci. 2010 Mar 12;1(6):450-462. PubMed PMID: 20567609; PubMed Central PMCID: PMC2887711. 4. Everett PB, Senogles SE. D3 dopamine receptor signals to activation of phospholipase D through a complex with Rho. J Neurochem. 2010 Feb;112(4):963-71. doi: 10.1111/j.1471-4159.2009.06508.x. Epub 2009 Dec 18. PubMed PMID: 20021566.