TargetMol

SKF-83822

Product Code:
 
TAR-T24802
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24802-50mg50mg£870.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24802-100mg100mg£1,332.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SKF-83822 is an agonist of dopamine D1-like receptor.
CAS:
74115-08-5
Formula:
C20H22ClNO2
Molecular Weight:
343.85
Purity:
0.98
SMILES:
Cc1cccc(c1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12

References

1. Paci P, Gabriele S, Ris L. A new method allowing long-term potentiation recordings in hippocampal organotypic slices. Brain Behav. 2017 Apr 12;7(5):e00692. doi: 10.1002/brb3.692. eCollection 2017 May. PubMed PMID: 28523233; PubMed Central PMCID: PMC5434196. 2. Abraham AD, Neve KA, Lattal KM. Activation of D1/5 Dopamine Receptors: A Common Mechanism for Enhancing Extinction of Fear and Reward-Seeking Behaviors. Neuropsychopharmacology. 2016 Jul;41(8):2072-81. doi: 10.1038/npp.2016.5. Epub 2016 Jan 14. PubMed PMID: 26763483; PubMed Central PMCID: PMC4908654. 3. Komal P, Estakhr J, Kamran M, Renda A, Nashmi R. cAMP-dependent protein kinase inhibits ?7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors. J Physiol. 2015 Aug 15;593(16):3513-32. doi: 10.1113/JP270469. Epub 2015 Jun 25. PubMed PMID: 25990637; PubMed Central PMCID: PMC4560582. 4. Gildea JJ, Shah IT, Van Sciver RE, Israel JA, Enzensperger C, McGrath HE, Jose PA, Felder RA. The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport. Kidney Int. 2014 Jul;86(1):118-26. doi: 10.1038/ki.2014.5. Epub 2014 Feb 19. PubMed PMID: 24552847; PubMed Central PMCID: PMC4077925.