TargetMol

VCC234718

Product Code:
 
TAR-T24933
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24933-5mg5mg£850.00
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Quantity:
TAR-T24933-50mg50mg£1,661.00
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Quantity:
TAR-T24933-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
VCC234718 is an IMPDH inhibitor. VCC234718 showed growth inhibitory activity against Mycobacterium tuberculosis. VCC234718 inhibits Mtb GuaB2 (Ki: 100 nM).
CAS:
1278553-16-4
Formula:
C20H25N3O3S
Molecular Weight:
387.5
Purity:
0.98
SMILES:
O=C(C1CCCCC1)N1CCN(CC1)S(=O)(=O)c1cccc2cnccc12

References

1. Shapiro AB, Gao N, Jahi? H, Carter NM, Chen A, Miller AA. Reversibility of Covalent, Broad-Spectrum Serine ?-Lactamase Inhibition by the Diazabicyclooctenone ETX2514. ACS Infect Dis. 2017 Nov 10;3(11):833-844. doi: 10.1021/acsinfecdis.7b00113. Epub 2017 Aug 28. PubMed PMID: 28835096. 2. Singh V, Donini S, Pacitto A, Sala C, Hartkoorn RC, Dhar N, Keri G, Ascher DB, Mond?sert G, Vocat A, Lupien A, Sommer R, Vermet H, Lagrange S, Buechler J, Warner DF, McKinney JD, Pato J, Cole ST, Blundell TL, Rizzi M, Mizrahi V. The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis. ACS Infect Dis. 2017 Jan 13;3(1):5-17. doi: 10.1021/acsinfecdis.6b00102. Epub 2016 Sep 8. PubMed PMID: 27726334; PubMed Central PMCID: PMC5241705.