TargetMol

Virodhamine trifluoroacetate

Product Code:
 
TAR-T24939
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24939-5mg5mg£850.00
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TAR-T24939-50mg50mg£1,661.00
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TAR-T24939-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Virodhamine trifluoroacetate is an antagonist of endogenous cannabinoid receptor mixed that acts by being a full agonist at GPR55 and CB2 and partial antagonist at CB1.
CAS:
1415264-56-0
Formula:
C24H38F3NO4
Molecular Weight:
461.566
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.CCCCCC=C/CC=C/CC=C/CC=C/CCCC(=O)OCCN

References

1. Hillard CJ, Huang H, Vogt CD, Rodrigues BE, Neumann TS, Sem DS, Schroeder F, Cunningham CW. Endocannabinoid Transport Proteins: Discovery of Tools to Study Sterol Carrier Protein-2. Methods Enzymol. 2017;593:99-121. doi: 10.1016/bs.mie.2017.06.017. Epub 2017 Jul 17. PubMed PMID: 28750817. 2. Pertwee RG. Endocannabinoids and Their Pharmacological Actions. Handb Exp Pharmacol. 2015;231:1-37. doi: 10.1007/978-3-319-20825-1_1. Review. PubMed PMID: 26408156. 3. Hind WH, Tufarelli C, Neophytou M, Anderson SI, England TJ, O'Sullivan SE. Endocannabinoids modulate human blood-brain barrier permeability in vitro. Br J Pharmacol. 2015 Jun;172(12):3015-27. doi: 10.1111/bph.13106. Epub 2015 Apr 10. PubMed PMID: 25651941; PubMed Central PMCID: PMC4459020. 4. Brantl SA, Khandoga AL, Siess W. Activation of platelets by the endocannabinoids 2-arachidonoylglycerol and virodhamine is mediated by their conversion to arachidonic acid and thromboxane A2, not by activation of cannabinoid receptors. Platelets. 2014;25(6):465-6. doi: 10.3109/09537104.2013.835040. Epub 2013 Oct 8. Review. PubMed PMID: 24102401.