TargetMol

VU0431316

Product Code:
 
TAR-T24947
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24947-5mg5mg£850.00
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TAR-T24947-50mg50mg£1,661.00
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Quantity:
TAR-T24947-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.
CAS:
1620203-63-5
Formula:
C14H9ClN6O2
Molecular Weight:
328.72
Purity:
0.98
SMILES:
Clc1ccnc(c1)C(=O)Nc1cncc(Oc2cncnc2)n1

References

1. Bates BS, Rodriguez AL, Felts AS, Morrison RD, Venable DF, Blobaum AL, Byers FW, Lawson KP, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Emmitte KA. Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3307-14. doi: 10.1016/j.bmcl.2014.06.003. Epub 2014 Jun 11. PubMed PMID: 24969015; PubMed Central PMCID: PMC4090943.