TargetMol

11-Oxahomoaminopterin

Product Code:
 
TAR-T24966
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24966-5mg5mg£1,653.00
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TAR-T24966-50mg50mg£3,267.00
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TAR-T24966-100mg100mg£4,488.00
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This product comes from: United States.
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Further Information

Bioactivity:
11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.
CAS:
78520-72-6
Formula:
C20H21N7O6
Molecular Weight:
455.431
Purity:
0.98
SMILES:
Nc1nc(N)c2nc(CCOc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

References

1. Nair MG, Bridges TW, Henkel TJ, Kisliuk RL, Gaumont Y, Sirotnak FM. Folate analogues altered in the C9-N10 bridge region. 18. Synthesis and antitumor evaluation of 11-oxahomoaminopterin and related compounds. J Med Chem. 1981 Sep;24(9):1068-73. PubMed PMID: 6793726.