TargetMol

7ETMC

Product Code:
 
TAR-T24988
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24988-5mg5mg£850.00
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TAR-T24988-50mg50mg£1,661.00
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Quantity:
TAR-T24988-100mg100mg£2,079.00
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Further Information

Bioactivity:
7ETMC is a selective Human Cytochrome P450s 1A1 and 1A2 inhibitor. 7ETMC showed IC50s of 0.46 μM and 0.50 μM for P450s 1A1 and 1A2 in the first six minutes, respectively, and did not show any inhibition activity for P450s 2A6 and 2B1 even at the dose of 50 μM.
CAS:
1370702-83-2
Formula:
C14H12O2
Molecular Weight:
212.248
Purity:
0.98
SMILES:
Cc1c(C)c(=O)oc2c(C)c(ccc12)C#C

References

1. Liu J, Nguyen TT, Dupart PS, Sridhar J, Zhang X, Zhu N, Stevens CL, Foroozesh M. 7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and
1A2. Chem Res Toxicol. 2012 May 21;25(5):1047-57. doi: 10.1021/tx300023p. Epub 2012 Apr 10. PubMed PMID: 22443586; PubMed Central PMCID: PMC3358478.