TargetMol

8-Deazahomofolic acid

Product Code:
 
TAR-T24991
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24991-5mg5mg£930.00
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TAR-T24991-50mg50mg£1,821.00
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Quantity:
TAR-T24991-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.
CAS:
111113-73-6
Formula:
C21H22N6O6
Molecular Weight:
454.443
Purity:
0.98
SMILES:
Nc1nc(=O)c2nc(CCNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2[nH]1

References

1. DeGraw JI, Colwell WT, Brown VH, Sato M, Kisliuk RL, Gaumont Y, Thorndike J, Sirotnak FM. Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative. J Med Chem. 1988 Jan;31(1):150-3. PubMed PMID: 3121855.