TargetMol

Asimicin

Product Code:
 
TAR-T25115
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25115-5mg5mg£3,099.00
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TAR-T25115-50mg50mg£6,159.00
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Quantity:
TAR-T25115-100mg100mg£8,825.00
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This product comes from: United States.
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Further Information

Bioactivity:
Asimicin is a effective complex I inhibitor.
CAS:
102989-24-2
Formula:
C37H66O7
Molecular Weight:
622.928
Purity:
0.98
SMILES:
CCCCCCCCCC[C@@H](O)[C@H]1CC[C@@H](O1)[C@H]1CC[C@@H](O1)[C@H](O)CCCCCCCCCC[C@@H](O)CC1=C[C@H](C)OC1=O

References

1. Mangal M, Khan MI, Agarwal SM. Acetogenins as Potential Anticancer Agents. Anticancer Agents Med Chem. 2015;16(2):138-59. Review. PubMed PMID: 26118710. 2. Nakamaru-Ogiso E, Han H, Matsuno-Yagi A, Keinan E, Sinha SC, Yagi T, Ohnishi T. The ND2 subunit is labeled by a photoaffinity analogue of asimicin, a potent complex I inhibitor. FEBS Lett. 2010 Mar 5;584(5):883-8. doi: 10.1016/j.febslet.2010.01.004. Epub 2010 Jan 13. PubMed PMID: 20074573; PubMed Central PMCID: PMC2836797. 3. Zhao GX, Miesbauer LR, Smith DL, McLaughlin JL. Asimin, asiminacin, and asiminecin: novel highly cytotoxic asimicin isomers from Asimina triloba. J Med Chem. 1994 Jun 24;37(13):1971-6. PubMed PMID: 8027979. 4. Avedissian H, Sinha SC, Yazbak A, Sinha A, Neogi P, Sinha SC, Keinan E. Total synthesis of asimicin and bullatacin. J Org Chem. 2000 Sep 22;65(19):6035-51. PubMed PMID: 10987938.