TargetMol

DCCCyb

Product Code:
 
TAR-T25292
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25292-5mg5mg£850.00
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Further Information

Bioactivity:
DCCCyb is an orally bioavailable and selective GlyT1 Inhibitor. DCCCyb demonstrated excellent in vivo occupancy of GlyT1 transporters in rhesus monkeys as determined by the displacement of a PET tracer ligand.
CAS:
1236046-15-3
Formula:
C22H29Cl2NO3S
Molecular Weight:
458.44
Purity:
0.98
SMILES:
Clc1ccc(C(=O)NC[C@]2(CC3CC3)CC[C@@H](CC2)S(=O)(=O)CC2CC2)c(Cl)c1

References

1. Blackaby WP, Lewis RT, Thomson JL, Jennings AS, Goodacre SC, Street LJ, MacLeod AM, Pike A, Wood S, Thomas S, Brown TA, Smith A, Pillai G, Almond S, Guscott MR, Burns HD, Eng W, Ryan C, Cook J, Hamill TG. Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1. ACS Med Chem Lett. 2010 Jun 25;1(7):350-4. doi: 10.1021/ml1001085. eCollection 2010 Oct 14. PubMed PMID: 24900218; PubMed Central PMCID: PMC4007840.