TargetMol

Jmv 320

Product Code:
 
TAR-T25552
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T25552-5mg5mg£850.00
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Further Information

Bioactivity:
Jmv 320 is a highly selective gastrin receptor and cholecystokinin receptor antagonist. It is a cyclic cholecystokinin-8 analog in which positions 28 and 31 have been replaced by Lys, with their side chains bridged by a succinic moiety.
CAS:
130582-10-4
Formula:
C53H67N11O13
Molecular Weight:
1066.183
Purity:
0.98
SMILES:
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCCNC(=O)CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CNC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

References

1. Witte DG, Nadzan AM, Martinez J, Rodriguez M, Lin CW. Characterization of the novel CCK analogs JMV-180, JMV-320, and JMV-332 in H345 cells. Peptides. 1992 Nov-Dec;13(6):1227-32. PubMed PMID: 1337381. 2. Hadjiivanova C, Kehayov R, Petkov VV, Amblard M, Martinez J. Behavioral effects of the cyclic cholecystokinin peptide analogue JMV-320. Peptides. 1995;16(5):815-9. PubMed PMID: 7479320. 3. Ishizuka J, Martinez J, Townsend CM Jr, Thompson JC. The effect of gastrin on growth of human stomach cancer cells. Ann Surg. 1992 May;215(5):528-34. PubMed PMID: 1616389; PubMed Central PMCID: PMC1242491. 4. Lignon MF, Bernad N, Martinez J. Cholecystokinin receptors in cells of the immune system. Ann N Y Acad Sci. 1994 Mar 23;713:334-7. PubMed PMID: 8185180.