TargetMol

Ketohypoglycin

Product Code:
 
TAR-T25572
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T25572-5mg5mgEnquire
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Further Information

Bioactivity:
Ketohypoglycin has been utilized to study the inhibition of gluconeogenesis in isolated rat liver cells.
CAS:
5746-24-7
Formula:
C7H8O3
Molecular Weight:
140.138
Purity:
0.98
SMILES:
OC(=O)C(=O)CC1CC1=C

References

1. Kean EA, Pogson CI. Inhibition of gluconeogenesis in isolated rat liver cells by methylenecyclopropylpyruvate (ketohypoglycin). Biochem J. 1979 Sep 15;182(3):789-96. PubMed PMID: 518564; PubMed Central PMCID: PMC1161413. 2. Marusich JA, Grant KR, Blough BE, Wiley JL. Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. Neurotoxicology. 2012 Oct;33(5):1305-13. doi: 10.1016/j.neuro.2012.08.003. Epub 2012 Aug 23. PubMed PMID: 22922498; PubMed Central PMCID: PMC3475178. 3. Kler RS, Sherratt HS, Turnbull DM. The measurement of mitochondrial beta-oxidation by release of 3H2O from [9,10-3H]hexadecanoate: application to skeletal muscle and the use of inhibitors as models of metabolic disease. Biochem Med Metab Biol. 1992 Apr;47(2):145-56. PubMed PMID: 1515172. 4. Billington D, Sherratt HS. Hypoglycin and metabolically related inhibitors. Methods Enzymol. 1981;72:610-6. PubMed PMID: 7311858.