TargetMol

Kinamycin B

Product Code:
 
TAR-T25581
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25581-5mg5mg£2,938.00
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TAR-T25581-50mg50mg£5,838.00
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TAR-T25581-100mg100mg£8,344.00
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Further Information

Bioactivity:
Kinamycin B is an antibacterial agent with anticancer activity.
CAS:
35303-13-0
Formula:
C20H16N2O8
Molecular Weight:
412.354
Purity:
0.98
SMILES:
CC(=O)OC1(C)C(O)C(O)c2c(C1O)n(C#N)c1c2C(=O)c2cccc(O)c2C1=O

References

1. Wang B, Ren J, Li L, Guo F, Pan G, Ai G, Aigle B, Fan K, Yang K. Kinamycin biosynthesis employs a conserved pair of oxidases for B-ring contraction. Chem Commun (Camb). 2015 May 25;51(42):8845-8. doi: 10.1039/c5cc01986a. PubMed PMID: 25920893. 2. Woo CM, Gholap SL, Lu L, Kaneko M, Li Z, Ravikumar PC, Herzon SB. Development of enantioselective synthetic routes to (-)-kinamycin F and (-)-lomaiviticin aglycon. J Am Chem Soc. 2012 Oct 17;134(41):17262-73. doi: 10.1021/ja307497h. Epub 2012 Oct 3. PubMed PMID: 23030272; PubMed Central PMCID: PMC3505684. 3. Gould SJ, Melville CR, Cone MC, Chen J, Carney JR. Kinamycin Biosynthesis. Synthesis, Isolation, and Incorporation of Stealthin C, an Aminobenzo[b]fluorene. J Org Chem. 1997 Jan 24;62(2):320-324. PubMed PMID: 11671405. 4. Kumamoto T. [Synthetic studies on kinamycin antibiotics]. Yakugaku Zasshi. 2010 Nov;130(11):1535-41. Review. Japanese. PubMed PMID: 21048414.