TargetMol

Lactivicin

Product Code:
 
TAR-T25597
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T25597-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Lactivicin is a non-beta-lactam antibiotic that acts by binding to penicillin-binding proteins.
CAS:
107167-31-7
Formula:
C10H12N2O7
Molecular Weight:
272.213
Purity:
0.98
SMILES:
CC(=O)NC1CON(C1=O)C1(CCC(=O)O1)C(O)=O

References

1. Starr J, Brown MF, Aschenbrenner L, Caspers N, Che Y, Gerstenberger BS, Huband M, Knafels JD, Lemmon MM, Li C, McCurdy SP, McElroy E, Rauckhorst MR, Tomaras AP, Young JA, Zaniewski RP, Shanmugasundaram V, Han S. Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. J Med Chem. 2014 May 8;57(9):3845-55. doi: 10.1021/jm500219c. Epub 2014 Apr 21. PubMed PMID: 24694215. 2. Nozaki Y, Katayama N, Harada S, Ono H, Okazaki H. Lactivicin, a naturally occurring non-beta-lactam antibiotic having beta-lactam-like action: biological activities and mode of action. J Antibiot (Tokyo). 1989 Jan;42(1):84-93. PubMed PMID: 2493440. 3. Calvopi?a K, Umland KD, Rydzik AM, Hinchliffe P, Brem J, Spencer J, Schofield CJ, Avison MB. Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4170-5. doi: 10.1128/AAC.00371-16. Print 2016 Jul. PubMed PMID: 27139464; PubMed Central PMCID: PMC4914698. 4. Tamura N, Matsushita Y, Kawano Y, Yoshioka K. Synthesis and antibacterial activity of lactivicin derivatives. Chem Pharm Bull (Tokyo). 1990 Jan;38(1):116-22. PubMed PMID: 2337934.