TargetMol

LAQ 824

Product Code:
 
TAR-T25629
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25629-5mg5mg£850.00
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Further Information

Bioactivity:
LAQ 824 is an inhibitor of histone deacetylase.
CAS:
591207-53-3
Formula:
C22H25N3O3
Molecular Weight:
379.46
Purity:
0.98
SMILES:
OCCN(CCc1cc2ccccc2[nH]1)Cc1ccc(C=CC(=O)NO)cc1

References

1. Rosato RR, Almenara JA, Maggio SC, Coe S, Atadja P, Dent P, Grant S. Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions. Mol Cancer Ther. 2008 Oct;7(10):3285-97. doi: 10.1158/1535-7163.MCT-08-0385. PubMed PMID: 18852132; PubMed Central PMCID: PMC2586957. 2. Ganai SA. Strategy for enhancing the therapeutic efficacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance. Arch Pharm Res. 2015 Oct 19. [Epub ahead of print] PubMed PMID: 26481010.