TargetMol

Levonantradol

Product Code:
 
TAR-T25696
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25696-5mg5mg£1,167.00
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Further Information

Bioactivity:
Levonantradol is a synthetic cannabinoid analog of dronabinol (Marinol). It shows antiemetic and analgesic effects via activation of CB1 and CB2 cannabinoid receptors.
CAS:
71048-87-8
Formula:
C27H35NO4
Molecular Weight:
437.58
Purity:
0.98
SMILES:
[H][C@@]12CC[C@@H](O)C[C@@]1([H])c1c(N[C@H]2C)cc(O[C@H](C)CCCc2ccccc2)cc1OC(C)=O

References

1. Sheshenev AE, Boltukhina EV, Hii KK. Levonantradol: asymmetric synthesis and structural analysis. Chem Commun (Camb). 2013 May 7;49(35):3685-7. doi: 10.1039/c3cc41388h. Epub 2013 Mar 27. PubMed PMID: 23535893. 2. Young AM, Katz JL, Woods JH. Behavioral effects of levonantradol and nantradol in the rhesus monkey. J Clin Pharmacol. 1981 Aug-Sep;21(S1):348S-360S. PubMed PMID: 6271836. 3. Costa E, Cheney DL, Murray TF. Levonantradol-induced inhibition of acetylcholine turnover in rat hippocampus and striatum. J Clin Pharmacol. 1981 Aug-Sep;21(S1):256S-261S. PubMed PMID: 6271831. 4. Heim ME, Romer W, Queisser W. Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting. J Clin Pharmacol. 1981 Aug-Sep;21(S1):86S-89S. PubMed PMID: 7298877.