TargetMol

Linearol

Product Code:
 
TAR-T25735
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25735-5mg5mg£850.00
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Further Information

Bioactivity:
Linearol is a diterpene found in Sideritis L. spp. (Lamiaceae) with a broad range of demonstrated properties including antioxidant, anti-inflammatory, and anti-apoptotic activities.
CAS:
37720-82-4
Formula:
C22H34O4
Molecular Weight:
362.51
Purity:
0.98
SMILES:
CC(=O)OC[C@@]1(C)[C@H](O)CC[C@@]2(C)[C@@H]3CC[C@H]4C[C@]3(CC4=C)[C@@H](O)CC12

References

1. Gonz?lez-Burgos E, Duarte AI, Carretero ME, Moreira PI, G?mez-Serranillos MP. Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions. Pharm Biol. 2016;54(4):705-11. doi: 10.3109/13880209.2015.1072829. Epub 2015 Oct 1. PubMed PMID: 26427521. 2. Gonz?lez-Burgos E, Carretero ME, G?mez-Serranillos MP. Involvement of Nrf2 signaling pathway in the neuroprotective activity of natural kaurane diterpenes. Neuroscience. 2013 Feb 12;231:400-12. doi: 10.1016/j.neuroscience.2012.10.018. Epub 2012 Oct 16. Erratum in: Neuroscience. 2014 Jun6;269():131. PubMed PMID: 23079631. 3. Gonz?lez-Burgos E, Carretero ME, G?mez-Serranillos MP. Kaurane diterpenes from Sideritis spp. exert a cytoprotective effect against oxidative injury that is associated with modulation of the Nrf2 system. Phytochemistry. 2013 Sep;93:116-23. doi: 10.1016/j.phytochem.2013.03.017. Epub 2013 May 2. PubMed PMID: 23642391. 4. Bruno M, Rosselli S, Pibiri I, Kilgore N, Lee KH. Anti-HIV agents derived from the ent-kaurane diterpenoid linearol. J Nat Prod. 2002 Nov;65(11):1594-7. PubMed PMID: 12444682.