TargetMol

Liriodenine methiodide

Product Code:
 
TAR-T25743
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T25743-5mg5mg£850.00
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TAR-T25743-50mg50mg£1,661.00
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Quantity:
TAR-T25743-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Liriodenine methiodide shows antibacterial and antifungal activity against several microorganisms.
CAS:
55974-07-7
Formula:
C18H12INO3
Molecular Weight:
417.202
Purity:
0.98
SMILES:
[I-].C[n+]1ccc2cc3OCOc3c3-c4ccccc4C(=O)c1c23

References

1. Hufford CD, Sharma AS, Oguntimein BO. Antibacterial and antifungal activity of liriodenine and related oxoaporphine alkaloids. J Pharm Sci. 1980 Oct;69(10):1180-3. PubMed PMID: 7420287. 2. Clark AM, Watson ES, Ashfaq MK, Hufford CD. In vivo efficacy of antifungal oxoaporphine alkaloids in experimental disseminated candidiasis. Pharm Res. 1987 Dec;4(6):495-8. PubMed PMID: 3508563. 3. Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Arch Pharm (Weinheim). 1991 Jan;324(1):29-33. PubMed PMID: 2043039. 4. Tripathi SK, Xu T, Feng Q, Avula B, Shi X, Pan X, Mask MM, Baerson SR, Jacob MR, Ravu RR, Khan SI, Li XC, Khan IA, Clark AM, Agarwal AK. Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis. J Biol Chem. 2017 Oct 6;292(40):16578-16593. doi: 10.1074/jbc.M117.781773. Epub 2017 Aug 18. PubMed PMID: 28821607; PubMed Central PMCID: PMC5633121.