TargetMol

Lorajmine

Product Code:
 
TAR-T25755
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25755-5mg5mg£1,974.00
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TAR-T25755-50mg50mg£3,910.00
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Quantity:
TAR-T25755-100mg100mg£5,452.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.
CAS:
47562-08-3
Formula:
C22H27ClN2O3
Molecular Weight:
402.92
Purity:
0.98
SMILES:
[H][C@@]12N(C)c3ccccc3[C@]11C[C@H]3[C@@H]([C@H]1OC(=O)CCl)[C@H]1C[C@]2([H])N3C(O)[C@H]1CC

References

1. Padrini R, Piovan D, Gaglione E, Zordan R, Ferrari M. Determination of lorajmine and its metabolite ajmaline in plasma and urine by a new high-performance liquid chromatographic method. Ther Drug Monit. 1992 Oct;14(5):391-6. PubMed PMID: 1448847. 2. Lanza GA, Rebuzzi AG, Santarelli P, Tamburi S, Lucente M. [Bidirectional tachycardia during therapy with lorajmine]. Cardiologia. 1989 Oct;34(10):893-6. Italian. PubMed PMID: 2605577. 3. Furlanello F, Gramegna L, Dal Forno P, Vergara G, Bettini R, Inama G, Disertori M. Worsening of arrhythmias during pharmacological treatment. G Ital Cardiol. 1984 Oct;14(10):798-803. PubMed PMID: 6440827. 4. Cafiero M, Buono G, D'Oriano R, Landmann E, Santoro R. [On the effects of lorajmine on ventricular and supraventricular extrasystolic arrhythmias. Study with the Holter method]. Minerva Cardioangiol. 1984 Jan-Feb;32(1-2):59-66. Italian. PubMed PMID: 6201786.