TargetMol

ML400

Product Code:
 
TAR-T25824
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25824-1mg1mg£208.00
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TAR-T25824-5mg5mg£326.00
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TAR-T25824-1mL1 mL * 10 mM (in DMSO)£402.00
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TAR-T25824-10mg10mg£491.00
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TAR-T25824-25mg25mg£752.00
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TAR-T25824-50mg50mg£1,010.00
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TAR-T25824-100mg100mg£1,340.00
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TAR-T25824-500mg500mg£2,609.00
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This product comes from: United States.
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Further Information

Bioactivity:
ML400 is an LMPTP allosteric inhibitor. ML400 is potent(EC50?1μM) and selective against other phosphatases, and displays good cell-based activity as well as rodent pharmacokinetics.
CAS:
1908414-42-5
Formula:
C24H29N3O
Molecular Weight:
375.516
Pathway:
Metabolism
Purity:
0.98
SMILES:
COc1ccc(cc1)-c1cc(NCCCN2CCCCC2)c2ccccc2n1
Target:
Phosphatase

References

1. Ardecky RJ, Hedrick MP, Stanford SM, Bliss MR, Zou J, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Mangravita-Novo A, Salaniwal S, Kung P, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Bottini N. Allosteric Small Molecule Inhibitors of LMPTP. 2014 Apr 15 [updated 2015 Jan 16]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Available from http://www.ncbi.nlm.nih.gov/books/NBK280042/ PubMed PMID: 25834896.